LPAR1 HEK293
CBP71677
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产品数据库
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I. Background |
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| LPAR1（溶血磷脂酸受体1）是一种G蛋白偶联受体，其内源性配体为溶血磷脂酸（LPA）。它顺利获得偶联G(i/o)、G(12/13)和G(q)等多种G蛋白，介导细胞骨架重排、迁移、增殖及存活等信号，参与组织损伤修复和炎症反应。LPAR1在神经病理性疼痛、肺纤维化及多种癌症中发挥重要作用，是潜在的药物研发靶点。 | |
| II. Description | |
| LPAR1 HEK293 细胞，在 HEK293 细胞的基础上，稳定表达人LPAR1。 | |
| III. Introduction | |
| Expressed gene: |
LPAR1
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| Host Cell: |
HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
DMEM + 10% FBS + 2 μg/ml Puromycin
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| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Transducer: | Gi/Go & Gq |
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IV. Representative Data
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